Plant Transcription Factor Database
Previous version: v3.0
Raphanus sativus
BES1 Family
Species TF ID Description
Rsa1.0_00015.1_g00034.1BES1 family protein
Rsa1.0_00037.1_g00028.1BES1 family protein
Rsa1.0_00119.1_g00020.1BES1 family protein
Rsa1.0_00269.1_g00015.1BES1 family protein
Rsa1.0_01214.1_g00002.1BES1 family protein
Rsa1.0_01388.1_g00008.1BES1 family protein
Rsa1.0_01419.1_g00018.1BES1 family protein
Rsa1.0_02199.1_g00005.1BES1 family protein
Rsa1.0_02245.1_g00004.1BES1 family protein
Rsa1.0_02929.1_g00001.1BES1 family protein
Rsa1.0_03168.1_g00005.1BES1 family protein
Rsa1.0_04081.1_g00003.1BES1 family protein
Rsa1.0_05242.1_g00003.1BES1 family protein
Rsa1.0_05436.1_g00002.1BES1 family protein
Rsa1.0_14168.1_g00001.1BES1 family protein
BES1 Family Introduction

Brassinosteroids (BRs) signal through a plasma membrane-localized receptor kinase to regulate plant growth and development. We showed previously that a novel protein, BES1(BRI1-EMS-SUPPRESSOR 1), accumulates in the nucleus in response to BRs, where it plays a role in BR-regulated gene expression; however, the mechanism by which BES1 regulates gene expression is unknown. In this study, we dissect BES1 subdomains and establish that BES1 is a transcription factor that binds to and activates BR target gene promoters both in vitro and in vivo. BES1 interacts with a basic helix-loop-helix protein, BIM1, to synergistically bind to E box (CANNTG) sequences present in many BR-induced promoters. Loss-of-function and gain-of-function mutants of BIM1 and its close family members display BR response phenotypes. Thus, BES1 defines a new class of plant-specific transcription factors that cooperate with transcription factors such as BIM1 to regulate BR-induced genes.

Yin Y, Vafeados D, Tao Y, Yoshida S, Asami T, Chory J.
A new class of transcription factors mediates brassinosteroid-regulated gene expression in Arabidopsis.
Cell. 2005 Jan 28;120(2):249-59.
PMID: 15680330